BDBM444597 US10662186, Compound 133::US10988476, Compound I-133

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc3CN(CCN(C)CCNC(N)=N)CCc3n2)ncc1F

InChI Key InChIKey=PQWACVUXFPZERA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444597   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

US Patent
LigandPNGBDBM444597(US10662186, Compound 133 | US10988476, Compound I-...)
Affinity DataIC50:  78.2nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding

US Patent
LigandPNGBDBM444597(US10662186, Compound 133 | US10988476, Compound I-...)
Affinity DataIC50:  78.2nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent